Whole-Genome Sequencing (WGS) is an untargeted, unbiased next-generation sequencing (NGS) solution and the most comprehensive way to investigate the genome of any species.

For commercial applications, WGS can be used to “skim” the genome at shallow depth, identifying markers or haplotypes which can be used to impute larger.

For research applications, WGS provides valuable insights by analyzing datasets against existing reference information. These analyses produce genetic and structural information that is not possible with more narrow/targeted sequencing approaches.


  • Any species
  • Any sample size
  • Short & long reads
    • Illumina®
    • PacBio®

Where it all begins

  • Use WGS to identify the best regions for targeted Capture-Seq and Flex-Seq® Ex-L applications.

Tissue/DNA to FASTQ data, SNPs and more

  • Minimum 500 samples for DNA extraction
    • Agricultural applications only
  • Up to 4-week turnaround times

Also known as:

  • Shotgun sequencing
  • Whole-genome resequencing

WGS Workflow

Whole-genome sequencing involves fragmenting genomic DNA and sequencing the full genome via NGS. WGS can be utilized for:

  • Marker discovery
    • Single nucleotide polymorphisms (SNPs)
  • Haplotype phasing
  • Structural variant detection
    • InDels
  • Loci mapping
    • QTL identification
    • Gene identification
    • Causal genetic variants
  • Chloroplast & mitochondria sequencing
  • Phylogenetic analysis
  • De novo genome assembly

Whole-Genome Sequencing Technology

WGS is only the beginning

In addition to end-to-end WGS solutions, we provide specialized data analysis and bioinformatics support, including but not limited to:

  • Development of Capture-Seq solutions
  • Marker & structural variant discovery: SNPs & Indels
  • Haplotype phasing
  • Loci mapping: QTL & gene identification
  • Germplasm characterization & PCA studies
  • De novo genome assembly

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