Genome Depletion Sequencing (GD-Seq) is an enhanced version of whole-genome sequencing. Through novel improvements to WGS technology, GD-Seq is the ideal alternative to traditional non targeted sequencing applications.

GD-Seq depletes repetitive elements of the genome to produce datasets with improved sequencing of lower copy number, and more informative, regions when compared to whole-genome sequencing.


  • Any species
    • Results are dependent on genome repetitive content
  • Any sample size

Where it all begins

  • Use GD-Seq to identify the best regions for targeted
  • Capture-Seq and Flex-Seq® Ex-L applications.

Tissue/DNA to FASTQ data, SNPs and more

  • Minimum 500 samples for DNA extraction
    • Agricultural applications only
  • Up to 4-week turnaround times

Take genome skimming to the next level

GD-Seq minimizes waste by removing repetitive DNA elements and boosting coverage of the most informative, low copy genomic regions.

These advances over WGS technology improve exon coverage by up to 500% at equivalent sequencing resources, delivering a new level of cost-efficiency at any scale.

Learn more about GD-Seq

GD-Seq Technology

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GD-Seq is only the beginning

In addition to end-to-end GD-Seq solutions, we provide specialized data analysis and bioinformatics support, including but not limited to:

  • Marker & structural variant discovery: SNPs
  • Haplotype phasing
  • Loci mapping: QTL & gene identification
  • Germplasm characterization & PCA studies